|
Drug |
RAI |
ED |
NaR |
T1/2 |
IM/PO * |
IV * |
|
|
dexamethasone |
Decadron |
30 |
0.8 |
0 |
36-72 |
0.75-9 |
2.5-10 |
|
betamethasone |
Rinderon |
25 |
0.8 |
0 |
36-72 |
0.6-9 |
0.6-9 |
|
triamcinolone |
Kenacort-A |
5 |
4 |
0 |
12-36 |
40-80 |
-- |
|
methylprednisolone |
Solu-medrol |
5 |
4 |
0.5 |
12-36 |
4-48 |
10-40 |
|
prednisolone |
|
4 |
5 |
0.8 |
12-36 |
5-60 |
-- |
|
hydrocortisone |
Solu-cortef |
1 |
20 |
1 |
8-12 |
15-240 |
15-240 |
|
cortisone |
|
0.8 |
25 |
0.8 |
8-12 |
20-300 |
-- |
KEY:
RAI = Relative anti-inflammatory potency
ED = Dose equivalency mg (milligrams)
NaR = Sodium retention capacity
T1/2 = biological half-life (hours)
IM/PO = inflammatory disease usual intramuscular or oral dose range (mg/day)
IV = inflammatory disease usual intravenous range (mg/day)
* = steroid-responsive conditions and doses required show considerable inter-individual variation; doses listed are representative, not exhaustive or inclusive
** = a single parenteral dose 4 to 7 times the oral daily dose may provide control for 4 to 7 days up to 3 to 4 weeks
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